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SOT: Revolutionizing Treatment for Tick-Borne Diseases

May 2, 2025

Tick-borne illnesses like Lyme disease, Babesia, Bartonella, and Ehrlichia are some of the most challenging infections to treat. These stealthy pathogens often evade traditional therapies, leading to chronic symptoms that can persist for years. Fortunately, an exciting advancement in precision medicine— Supportive Oligonucleotide Therapy (SOT)—is offering new hope for those seeking lasting recovery and healing. Our Lyme specialist at the Functional Medicine Center of New Jersey, Dr. Nicole Anderson, scoured the globe to bring this technology to her children and is thankful to now offer it to our patients.

What is SOT?

Supportive Oligonucleotide Therapy (SOT) is a highly personalized treatment that uses small, lab-created strands of genetic material (called oligonucleotides) to block a pathogen’s ability to reproduce. Each SOT treatment is custom-made based on the exact infection of each patient.Instead of using broad-spectrum antibiotics, which often have detrimental affects on gut health and the immune system, SOT silences the infection at the genetic level, giving a patients’ body the chance to heal naturally.

How does SOT Work for Tick-Borne Illnesses?

Lyme disease and its common co-infections hide in biofilms, change forms and can burrow deep into tissues making them difficult to treat. SOT works differently than other methods traditionally used to treat tick-borne illnesses:
  • Identification – The first step is identifying the specific pathogens present for each patient using specialized lab testing
  • Sequencing – The genetic material of the pathogen is then analyzed to determine the specific sequence is uses to reproduce
  • Design – Scientists create a custom oligonucleotide that binds precisely to the genetic sequence, blocking the pathogen’s ability to reproduce
  • Delivery – Patients receive their unique SOT via intravenous infusion, which immediately seeks out and disrupts the targeted pathogen
  • Healing – As the infection loses its ability to reproduce, a patient’s immune system begins to regain strength and inflammation decreases

Benefits of SOT for Tick-Borne Illnesses:

  • Precision Without Collateral Damage – Traditional antibiotics can lead to gut issues, candida overgrowth, and weakened immunity. SOT targets the infection without harming healthy issues
  • Long-Term Action – One SOT infusion can remain active in the body for up to 6-9 months, helping to ensure the pathogens stay suppressed while a patient’s body rebuilds
  • Integrative with Holistic Healing – Due to its precision approach, SOT works well in conjunction with functional medicine plans that support detoxification, gut healing, and emotional health.
The fight against chronic Lyme disease and other tick-borne infections can feel endless. With Supportive Oligonucleotide Therapy, we offer our patients a way to treat these complex illnesses at their core – intelligently, precisely, and holistically. When incorporated into a comprehensive, individualized care plan, SOT can be the breakthrough therapy that unlocks profound and lasting healing.
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